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    uvs-1 UV-stimulated scaffold protein A homolog [ Caenorhabditis elegans ]

    Gene ID: 179158, updated on 9-Dec-2024

    Summary

    Official Symbol
    uvs-1
    Official Full Name
    UV-stimulated scaffold protein A homolog
    Primary source
    WormBase:WBGene00022812
    Locus tag
    CELE_ZK742.2
    See related
    AllianceGenome:WB:WBGene00022812
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Involved in response to UV and transcription-coupled nucleotide-excision repair. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in UV-sensitive syndrome. Orthologous to human UVSSA (UV stimulated scaffold protein A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See uvs-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (7801505..7804208, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene GLGPRPLRF-amide Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene Exportin-1 C-terminal domain-containing protein;Importin N-terminal domain-containing protein Neighboring gene NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to UV IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to UV IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to UV IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transcription-coupled nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transcription-coupled nucleotide-excision repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    UV-stimulated scaffold protein A homolog
    NP_505012.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7801505..7804208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072611.6NP_505012.2  UV-stimulated scaffold protein A homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23088
      Conserved Domains (1) summary
      pfam09740
      Location:389491
      DUF2043; Uncharacterized conserved protein (DUF2043)