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    lipl-8 Lipase [ Caenorhabditis elegans ]

    Gene ID: 190108, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lipl-8
    Official Full Name
    Lipase
    Primary source
    WormBase:WBGene00013050
    Locus tag
    CELE_Y50E8A.7
    See related
    AllianceGenome:WB:WBGene00013050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lipl-8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (14745684..14748708, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glycerol-3-phosphate dehydrogenase Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Nematode Specific Peptide family, group A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans. Sun Y, et al. Elife, 2020 Jun 2. PMID 32482227, Free PMC Article
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipase
    NP_506641.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14745684..14748708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074240.2 → NP_506641.1  Lipase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506641.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U276
      Conserved Domains (3) summary
      PLN02872
      Location:26 → 401
      PLN02872; triacylglycerol lipase
      pfam04083
      Location:26 → 89
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      pfam12695
      Location:71 → 193
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version

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