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    timm-17B.2 Translocase, Inner Mitochondrial Membrane [ Caenorhabditis elegans ]

    Gene ID: 183965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    timm-17B.2
    Official Full Name
    Translocase, Inner Mitochondrial Membrane
    Primary source
    WormBase:WBGene00017069
    Locus tag
    CELE_D2096.1
    See related
    AllianceGenome:WB:WBGene00017069
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See timm-17B.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (8396648..8397954)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C6 domain-containing protein Neighboring gene GAR domain-containing protein Neighboring gene pseudo Neighboring gene pseudo Neighboring gene F-box domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondria Retrograde Signaling and the UPR mt: Where Are We in Mammals? Arnould T, et al. Int J Mol Sci, 2015 Aug 6. PMID 26258774, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    contributes_to protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Translocase, Inner Mitochondrial Membrane
    NP_001294049.1
    • Product from WormBase gene class timm;
      Confirmed by transcript evidence
    NP_001367715.1
    • Product from WormBase gene class timm;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8396648..8397954
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380363.2 → NP_001367715.1  Translocase, Inner Mitochondrial Membrane [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19012
      Conserved Domains (1) summary
      cl02381
      Location:1 → 56
      Tim17; Tim17/Tim22/Tim23/Pmp24 family

    2. NM_001307120.4 → NP_001294049.1  Translocase, Inner Mitochondrial Membrane [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294049.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5LX78
    Nucleotide Protein
    Heading Accession and Version

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