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    • Showing Current items.

    C04E6.5 ubiquitinyl hydrolase 1 [ Caenorhabditis elegans ]

    Gene ID: 178977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C04E6.5
    Official Full Name
    ubiquitinyl hydrolase 1
    Primary source
    WormBase:WBGene00015422
    Locus tag
    CELE_C04E6.5
    See related
    AllianceGenome:WB:WBGene00015422
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in ERAD pathway and regulation of protein stability. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C04E6.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (5902133..5904843)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene HAD family phosphatase Neighboring gene Ground-like domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Glycoprotein 120

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of protein stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitinyl hydrolase 1
    NP_504537.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5902133..5904843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072136.4 → NP_504537.1  ubiquitinyl hydrolase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504537.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01467
      Conserved Domains (1) summary
      cd02673
      Location:146 → 513
      Peptidase_C19Q; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    Nucleotide Protein
    Heading Accession and Version

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