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    Y65B4A.2 Peptidase C1A papain C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171655, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y65B4A.2
    Official Full Name
    Peptidase C1A papain C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00022026
    Locus tag
    CELE_Y65B4A.2
    See related
    AllianceGenome:WB:WBGene00022026
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in membrane. Predicted to be active in extracellular space and lysosome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y65B4A.2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (638129..653988)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RNA helicase Neighboring gene ncRNA Neighboring gene Charged multivesicular body protein 6 Neighboring gene LIM zinc-binding domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene Cytidyltransferase-like domain-containing protein Neighboring gene Protein kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis involved in protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Peptidase C1A papain C-terminal domain-containing protein
    NP_001293245.1
    • Confirmed by transcript evidence
    NP_001293246.1
    • Confirmed by transcript evidence
    NP_490763.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      638129..653988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306316.3 → NP_001293245.1  Peptidase C1A papain C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293245.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLX0
      Conserved Domains (1) summary
      cd02620
      Location:153 → 431
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...

    2. NM_001306317.4 → NP_001293246.1  Peptidase C1A papain C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293246.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CLS8
      Conserved Domains (1) summary
      cd02620
      Location:166 → 444
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...

    3. NM_058362.5 → NP_490763.1  Peptidase C1A papain C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490763.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL59
      Conserved Domains (1) summary
      cd02620
      Location:139 → 417
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    Nucleotide Protein
    Heading Accession and Version

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