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    Y39G10AR.9 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171789, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y39G10AR.9
    Official Full Name
    WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00021467
    Locus tag
    CELE_Y39G10AR.9
    See related
    AllianceGenome:WB:WBGene00021467
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be part of proteasome complex. Orthologous to human PAAF1 (proteasomal ATPase associated factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y39G10AR.9 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (2307267..2308975)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene TPX2 domain-containing protein Neighboring gene Ectopic P granules protein 2 Neighboring gene Inner centromere protein ARK-binding domain-containing protein Neighboring gene 5-methylcytosine rRNA methyltransferase nsun-4 Neighboring gene Tubulin-specific chaperone A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of proteasome complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    WD_REPEATS_REGION domain-containing protein
    NP_001249132.1
    • Partially confirmed by transcript evidence
    NP_001249133.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2307267..2308975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001262203.3 → NP_001249132.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001249132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XR3
      Conserved Domains (2) summary
      sd00039
      Location:134 → 169
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:133 → 414
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001262204.2 → NP_001249133.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001249133.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SF15
      Conserved Domains (2) summary
      sd00039
      Location:116 → 151
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:115 → 396
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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