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    snf-1 Sodium: Neurotransmitter symporter Family [ Caenorhabditis elegans ]

    Gene ID: 172119, updated on 27-Dec-2024

    Summary

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    Official Symbol
    snf-1
    Official Full Name
    Sodium: Neurotransmitter symporter Family
    Primary source
    WormBase:WBGene00004900
    Locus tag
    CELE_W03G9.1
    See related
    AllianceGenome:WB:WBGene00004900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity and amino acid:sodium symporter activity. Predicted to be involved in glycine import across plasma membrane and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See snf-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (4980307..4983959)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Transmembrane protein Neighboring gene 1-alkyl-2-acetylglycerophosphocholine esterase Neighboring gene CILiary localization

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function. Jiang G, et al. J Biol Chem, 2005 Jan 21. PMID 15542610
    2. A database of Caenorhabditis elegans behavioral phenotypes. Yemini E, et al. Nat Methods, 2013 Sep. PMID 23852451, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Sodium: Neurotransmitter symporter Family
    NP_491491.2
    • Product from WormBase gene class snf;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4980307..4983959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059090.10 → NP_491491.2  Sodium: Neurotransmitter symporter Family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491491.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44752
      Conserved Domains (1) summary
      cl11976
      Location:21 → 554
      SNF; Sodium:neurotransmitter symporter family
    Nucleotide Protein
    Heading Accession and Version

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