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    ifas-2 Inducible FAScin Domain containing [ Caenorhabditis elegans ]

    Gene ID: 180128, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ifas-2
    Official Full Name
    Inducible FAScin Domain containing
    Primary source
    WormBase:WBGene00008615
    Locus tag
    CELE_F09C6.1
    See related
    AllianceGenome:WB:WBGene00008615
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in cytoplasm. Predicted to be active in actin cytoskeleton. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ifas-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (16887357..16888888, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Flagellar rod assembly protein/muramidase FlgJ Neighboring gene FlxA-like protein Neighboring gene F-box domain-containing protein Neighboring gene DUF38 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ifas-1 is upregulated by fungal infection in a GPA-12 and STA-2-independent manner in the Caenorhabditis elegans epidermis. Omi S, et al. MicroPubl Biol, 2021 May 25. PMID 34056565, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Inducible FAScin Domain containing
    NP_507266.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class ifas

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      16887357..16888888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074865.5 → NP_507266.1  Inducible FAScin Domain containing [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507266.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45327
      Conserved Domains (1) summary
      cd00257
      Location:106 → 223
      Fascin; Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an ...
    Nucleotide Protein
    Heading Accession and Version

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