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    Esp Epidermal stripes and patches [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42962, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Espprovided by FlyBase
    Official Full Name
    Epidermal stripes and patchesprovided by FlyBase
    Primary source
    FLYBASE:FBgn0013953
    Locus tag
    Dmel_CG7005
    See related
    AllianceGenome:FB:FBgn0013953
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7005; Dmel\CG7005
    Summary
    Predicted to enable sulfate transmembrane transporter activity. Involved in negative regulation of female receptivity, post-mating. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult fat body; amnioserosa primordium; extraembryonic structure; gut section; and head epidermis primordium. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Esp in Genome Data Viewer
    Location:
    96B1-96B1; 3-86 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24841935..24850412)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20667657..20676134)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45216 Neighboring gene sosie Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Nicastrin Neighboring gene Histone deacetylase 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
    2. Molecular evolution of the sex peptide network in Drosophila. McGeary MK, et al. J Evol Biol, 2020 May. PMID 31991034
    3. FOXO-regulated transcription restricts overgrowth of Tsc mutant organs. Harvey KF, et al. J Cell Biol, 2008 Feb 25. PMID 18299344, Free PMC Article
    4. A double-negative gene regulatory circuit underlies the virgin behavioral state. Garaulet DL, et al. Cell Rep, 2021 Jul 6. PMID 34233178, Free PMC Article
    5. Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye. Zhang T, et al. Dev Dyn, 2005 Nov. PMID 16145661

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sulfate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of female receptivity, post-mating IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sulfate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    epidermal stripes and patches
    Names
    CG7005-PA
    CG7005-PB
    Esp-PA
    Esp-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24841935..24850412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202353.2 → NP_001189282.1  epidermal stripes and patches, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189282.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U6Q2, Q9VC29
      Conserved Domains (3) summary
      cd07042
      Location:545 → 623
      STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
      TIGR00815
      Location:86 → 615
      sulP; high affinity sulphate transporter 1
      cl23746
      Location:103 → 520
      HCO3_cotransp; HCO3- transporter family

    2. NM_079766.4 → NP_524490.2  epidermal stripes and patches, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524490.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U6Q2, Q9VC29
      Related
      FBpp0084081
      Conserved Domains (3) summary
      cd07042
      Location:545 → 623
      STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
      TIGR00815
      Location:86 → 615
      sulP; high affinity sulphate transporter 1
      cl23746
      Location:103 → 520
      HCO3_cotransp; HCO3- transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U6Q2 Q9U6Q2
    Q9VC29 Q9VC29

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