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    Ugt303B1 UDP-glycosyltransferase family 303 member B1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42775, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt303B1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 303 member B1provided by FlyBase
    Primary source
    FLYBASE:FBgn0039086
    Locus tag
    Dmel_CG16732
    See related
    AllianceGenome:FB:FBgn0039086
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16732; Dmel\CG16732; UGT303B1
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt303B1 in Genome Data Viewer
    Location:
    95A1-95A1; 3-80 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23534900..23536710, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19360622..19362432, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene UDP-glycosyltransferase family 303 member B3 Neighboring gene UDP-glycosyltransferase family 303 member B2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
    2. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111
    3. Comparative analysis of the UDP-glycosyltransferase multigene family in insects. Ahn SJ, et al. Insect Biochem Mol Biol, 2012 Feb. PMID 22155036
    4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 303 member B1
    Names
    CG16732-PA
    CG16732-PB
    Ugt303B1-PA
    Ugt303B1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23534900..23536710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202343.1 → NP_001189272.1  UDP-glycosyltransferase family 303 member B1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189272.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JCZ9
      Conserved Domains (2) summary
      PHA03392
      Location:21 → 459
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:41 → 508
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    2. NM_142896.2 → NP_651153.1  UDP-glycosyltransferase family 303 member B1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651153.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VCL4
      Related
      FBpp0083811
      Conserved Domains (2) summary
      PHA03392
      Location:21 → 462
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:41 → 511
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JCZ9 A0A0B4JCZ9
    Q9VCL4 Q9VCL4

    Gene LinkOut

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