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    CG32344 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326208, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG32344provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052344
    Locus tag
    Dmel_CG32344
    See related
    AllianceGenome:FB:FBgn0052344
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg6994; CG6994; Dmel\CG32344; DmRH20
    Summary
    Predicted to enable RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in several structures, including anal pad primordium; dorsal pharyngeal muscle cell; embryonic anal pad; embryonic/larval midgut primordium; and gut section. Orthologous to human DDX54 (DEAD-box helicase 54). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32344 in Genome Data Viewer
    Location:
    61C1-61C1; 3-0.5 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (321233..324720, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (321233..324720, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 3 Neighboring gene four wheel drive Neighboring gene deadbeat Neighboring gene Ada2a-containing complex component 3 Neighboring gene Protein tyrosine phosphatase Meg Neighboring gene methuselah-like 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DDX56 Binds to Chikungunya Virus RNA To Control Infection. Taschuk F, et al. mBio, 2020 Oct 27. PMID 33109765, Free PMC Article
    2. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Chen CL, et al. Proc Natl Acad Sci U S A, 2015 Sep 29. PMID 26362788, Free PMC Article
    3. Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense. Moy RH, et al. Cell, 2014 Aug 14. PMID 25126784, Free PMC Article
    4. In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila. Wong SL, et al. Biochem Biophys Res Commun, 2005 Nov 18. PMID 16212942, Free PMC Article
    5. Evolution of intron/exon structure of DEAD helicase family genes in Arabidopsis, Caenorhabditis, and Drosophila. Boudet N, et al. Genome Res, 2001 Dec. PMID 11731501, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32344-PA
    NP_612028.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      321233..324720 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138184.5 → NP_612028.4  uncharacterized protein Dmel_CG32344 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612028.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY39
      Related
      FBpp0072475
      Conserved Domains (4) summary
      smart00487
      Location:54 → 243
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:263 → 384
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:41 → 243
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam08147
      Location:666 → 721
      DBP10CT; DBP10CT (NUC160) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SY39 Q8SY39

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