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    TAF1C-like TATA box-binding protein-associated factor RNA polymerase I subunit C-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37450, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TAF1C-likeprovided by FlyBase
    Official Full Name
    TATA box-binding protein-associated factor RNA polymerase I subunit C-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034631
    Locus tag
    Dmel_CG10496
    See related
    AllianceGenome:FB:FBgn0034631
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10496; Dmel\CG10496; TAF1Clike
    Summary
    Predicted to be involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase transcription factor SL1 complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TAF1C-like in Genome Data Viewer
    Location:
    57E6-57E8; 2-95 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21498903..21501732, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17386408..17389237, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene FK506-binding protein 14 Neighboring gene uncharacterized protein Neighboring gene Misexpression suppressor of KSR 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon. Fefelova EA, et al. Nucleic Acids Res, 2022 Jan 25. PMID 35037046, Free PMC Article
    2. Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage. Zhang Q, et al. Science, 2014 Jan 17. PMID 24436420, Free PMC Article
    3. FKBP14 is an essential gene that regulates Presenilin protein levels and Notch signaling in Drosophila. van de Hoef DL, et al. Development, 2013 Feb. PMID 23318643
    4. Distinct gene-selective roles for a network of core promoter factors in Drosophila neural stem cell identity. Neves A, et al. Biol Open, 2019 Apr 4. PMID 30948355, Free PMC Article
    5. Genetic screening for modifiers of the DREF pathway in Drosophila melanogaster: identification and characterization of HP6 as a novel target of DREF. Ida H, et al. Nucleic Acids Res, 2009 Apr. PMID 19136464, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleolar large rRNA transcription by RNA polymerase I IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase transcription factor SL1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TATA box-binding protein-associated factor RNA polymerase I subunit C-like
    Names
    CG10496-PA
    TAF1C-like-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21498903..21501732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137741.5 → NP_611585.1  TATA box-binding protein-associated factor RNA polymerase I subunit C-like [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611585.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2G5
      Related
      FBpp0071618
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2G5 Q9W2G5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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