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    CG32147 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 251690, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32147provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0047178
    Locus tag
    Dmel_CG32147
    See related
    AllianceGenome:FB:FBgn0047178
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE07960; Dmel\CG32147
    Summary
    Predicted to enable pyroglutamyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytosol. Is expressed in organism. Orthologous to several human genes including PGPEP1 (pyroglutamyl-peptidase I). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32147 in Genome Data Viewer
    Location:
    71B5-71B5; 3-42 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15143063..15144059, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15136163..15137159, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene small Cajal body-specific RNA : MeU5-U42 Neighboring gene Protein disulfide isomerase Neighboring gene antisense RNA:CR45396 Neighboring gene antisense RNA:CR45397 Neighboring gene Peroxin 3 Neighboring gene alpha1,3-fucosyltransferase A Neighboring gene Msh6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. Chen J, et al. Genome Res, 2008 Jan. PMID 18042644, Free PMC Article
    2. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article
    3. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article
    4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables pyroglutamyl-peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32147-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15143063..15144059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168616.2 → NP_730035.1  uncharacterized protein Dmel_CG32147 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730035.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZB7
      Related
      FBpp0075400
      Conserved Domains (1) summary
      cd00501
      Location:7 → 222
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZB7 Q8SZB7

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