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    128up upstream of RpIII128 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36288, updated on 9-Dec-2024

    Summary

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    Official Symbol
    128upprovided by FlyBase
    Official Full Name
    upstream of RpIII128provided by FlyBase
    Primary source
    FLYBASE:FBgn0010339
    Locus tag
    Dmel_CG8340
    See related
    AllianceGenome:FB:FBgn0010339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8340; Dmel\CG8340; GBP; Gtp-bp; GTP-bp; X71866
    Summary
    Enables GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytoplasm. Is expressed in adult head. Orthologous to human DRG1 (developmentally regulated GTP binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See 128up in Genome Data Viewer
    Location:
    48D8-48D8; 2-65 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12037298..12038851)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7924803..7926356)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene precocious dissociation of sisters 5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene RNA polymerase III subunit B Neighboring gene DNA fragmentation factor-related protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Chowdhury R, et al. Sci Rep, 2022 Apr 11. PMID 35410347, Free PMC Article
    2. The gene upstream of DmRP128 codes for a novel GTP-binding protein of Drosophila melanogaster. Sommer KA, et al. Mol Gen Genet, 1994 Feb. PMID 8121394
    3. How intron splicing affects the deletion and insertion profile in Drosophila melanogaster. Ptak SE, et al. Genetics, 2002 Nov. PMID 12454069, Free PMC Article
    4. Proteomics Screen Identifies Class I Rab11 Family Interacting Proteins as Key Regulators of Cytokinesis. Laflamme C, et al. Mol Cell Biol, 2017 Feb 1. PMID 27872148, Free PMC Article
    5. Estimation of isolation times of the island species in the Drosophila simulans complex from multilocus DNA sequence data. McDermott SR, et al. PLoS One, 2008 Jun 18. PMID 18560591, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    upstream of RpIII128
    Names
    128up-PA
    CG8340-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12037298..12038851
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080485.6 → NP_536733.1  upstream of RpIII128 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_536733.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P32234, Q9V648
      Related
      FBpp0087084
      Conserved Domains (1) summary
      COG1163
      Location:1 → 367
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32234.2 P32234

    Gene LinkOut

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