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    Drsl4 Drosomycin-like 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317954, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Drsl4provided by FlyBase
    Official Full Name
    Drosomycin-like 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0052282
    Locus tag
    Dmel_CG32282
    See related
    AllianceGenome:FB:FBgn0052282
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32282; Dmel\CG32282; dro-4; Dro-4; dro4; Dro4; dros4; Drs-lF
    Summary
    Involved in defense response to fungus. Predicted to be located in extracellular region. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Drsl4 in Genome Data Viewer
    Location:
    63D1-63D1; 3-8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3315620..3315942)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3315620..3315942)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Drosomycin-like 2 Neighboring gene Drosomycin-like 3 Neighboring gene Drosomycin-like 5 Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression, antiparasitic activity, and functional evolution of the drosomycin family. Tian C, et al. Mol Immunol, 2008 Sep. PMID 18657321
    2. Functional role of charged residues in drosomycin, a Drosophila antifungal peptide. Zhang Z, et al. Dev Comp Immunol, 2010 Sep. PMID 20420852
    3. Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster. Yang WY, et al. Gene, 2006 Sep 1. PMID 16824706
    4. The genetic basis of variation in sexual aggression: Evolution versus social plasticity. Scott AM, et al. Mol Ecol, 2022 May. PMID 35313034
    5. Adult Drosophila melanogaster evolved for antibacterial defense invest in infection-induced expression of both humoral and cellular immunity genes. Ye YH, et al. BMC Res Notes, 2011 Aug 23. PMID 21859495, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to fungus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response to fungus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Drosomycin-like 4
    Names
    CG32282-PA
    Drosomycin-4
    Drosomycin-like F
    Drsl4-PA
    drosmycin-4
    drosomycin
    drosomycin 4
    drosomycin-F

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3315620..3315942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168021.3 → NP_728862.1  Drosomycin-like 4 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728862.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7FNM4, Q8IRD6
      Related
      FBpp0072925
      Conserved Domains (1) summary
      pfam00304
      Location:28 → 70
      Gamma-thionin; Gamma-thionin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRD6 Q8IRD6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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