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    OXA1L OXA1L mitochondrial inner membrane protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39222, updated on 9-Dec-2024

    Summary

    Official Symbol
    OXA1Lprovided by FlyBase
    Official Full Name
    OXA1L mitochondrial inner membrane proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027615
    Locus tag
    Dmel_CG6404
    See related
    AllianceGenome:FB:FBgn0027615
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH02220; CG6404; Dmel\CG6404; OXA1
    Summary
    Predicted to enable membrane insertase activity. Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly and protein insertion into mitochondrial inner membrane from matrix. Located in mitochondrial crista and mitochondrial inner boundary membrane. Is expressed in adult head; embryonic/larval midgut; organism; and testis. Orthologous to human OXA1L (OXA1L mitochondrial inner membrane protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See OXA1L in Genome Data Viewer
    Location:
    67F1-67F1; 3-33 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10884261..10886471, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10877361..10879571, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene galla-2 Neighboring gene Cuticular protein 67Fa1 Neighboring gene Cuticular protein 67Fa2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables membrane insertase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables membrane insertase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables membrane insertase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial proton-transporting ATP synthase complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein insertion into mitochondrial inner membrane from matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein insertion into mitochondrial inner membrane from matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial crista IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in mitochondrial inner boundary membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in mitochondrial inner boundary membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    OXA1L mitochondrial inner membrane protein
    Names
    CG6404-PA
    CG6404-PB
    OXA1L-PA
    OXA1L-PB
    biogenesis protein OXA1
    inner membrane protein OXA1L

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      10884261..10886471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168424.2NP_729634.1  OXA1L mitochondrial inner membrane protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729634.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTC5, Q9Y171
      Related
      FBpp0076001
      Conserved Domains (1) summary
      TIGR03592
      Location:152342
      yidC_oxa1_cterm; membrane protein insertase, YidC/Oxa1 family, C-terminal domain
    2. NM_140160.3NP_648417.1  OXA1L mitochondrial inner membrane protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648417.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTC5, Q9Y171
      Related
      FBpp0076000, FBtr0076271
      Conserved Domains (1) summary
      TIGR03592
      Location:152342
      yidC_oxa1_cterm; membrane protein insertase, YidC/Oxa1 family, C-terminal domain