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    npr-16 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180643, updated on 9-Dec-2024

    Summary

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    Official Symbol
    npr-16
    Official Full Name
    G-protein coupled receptors family 1 profile domain-containing protein
    Primary source
    WormBase:WBGene00006864
    Locus tag
    CELE_F56B6.5
    See related
    AllianceGenome:WB:WBGene00006864
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in anal depressor muscle; neurons; ventral nerve cord; and vm1. Orthologous to human SSTR3 (somatostatin receptor 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See npr-16 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (3522780..3531862)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene HMG box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CC domain-containing protein Neighboring gene Glycogenin-1 Neighboring gene C2 domain-containing protein;RGS domain-containing protein;Regulator of G-protein signaling rgs-7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of regions of the Caenorhabditis elegans X chromosome containing vitellogenin genes. Heine U, et al. J Mol Biol, 1986 Apr 5. PMID 3735423
    2. Identification of novel target genes of CeTwist and CeE/DA. Wang P, et al. Dev Biol, 2006 May 15. PMID 16480708
    3. Cannabinoids activate the insulin pathway to modulate mobilization of cholesterol in C. elegans. Hernandez-Cravero B, et al. PLoS Genet, 2022 Nov. PMID 36346800, Free PMC Article
    4. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Styer KL, et al. Science, 2008 Oct 17. PMID 18801967, Free PMC Article
    5. A gene expression fingerprint of C. elegans embryonic motor neurons. Fox RM, et al. BMC Genomics, 2005 Mar 21. PMID 15780142, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G-protein coupled receptors family 1 profile domain-containing protein
    NP_001041258.1
    • Confirmed by transcript evidence
    NP_001041259.1
    • Confirmed by transcript evidence
    NP_001355489.1
    • Confirmed by transcript evidence
    NP_001355490.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3522780..3531862
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001368498.3 → NP_001355490.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A3B1DQQ4
      Conserved Domains (1) summary
      cd00637
      Location:45 → 305
      7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

    2. NM_001368499.4 → NP_001355489.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A3B1E8V2
      Conserved Domains (1) summary
      cd00637
      Location:45 → 305
      7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

    3. NM_001047793.6 → NP_001041258.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041258.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22995
      Conserved Domains (1) summary
      cd00637
      Location:35 → 295
      7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

    4. NM_001047794.5 → NP_001041259.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041259.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2V4S5
      Conserved Domains (1) summary
      cd00637
      Location:35 → 295
      7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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