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    scav-1 SCAVenger receptor (CD36 family) related [ Caenorhabditis elegans ]

    Gene ID: 180812, updated on 9-Dec-2024

    Summary

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    Official Symbol
    scav-1
    Official Full Name
    SCAVenger receptor (CD36 family) related
    Primary source
    WormBase:WBGene00015389
    Locus tag
    CELE_C03F11.3
    See related
    AllianceGenome:WB:WBGene00015389
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable scavenger receptor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be active in membrane. Orthologous to human SCARB1 (scavenger receptor class B member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See scav-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (5397699..5400584, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Small conductance calcium-activated potassium channel-like protein 3 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Coiled-coil domain-containing protein Neighboring gene tRNA-Met

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fungal pathogen recognition by scavenger receptors in nematodes and mammals. Means TK. Virulence, 2010 Jan-Feb. PMID 21178411, Free PMC Article
    2. Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. Means TK, et al. J Exp Med, 2009 Mar 16. PMID 19237602, Free PMC Article
    3. SCAV-3 affects apoptotic cell degradation in Caenorhabditis elegans. Ma A, et al. FEBS Open Bio, 2023 May. PMID 36947094, Free PMC Article
    4. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CED-1/SCARF1 and C03F11.3/CD36 are beta-glucan binding receptors and define an evolutionarily conserved pathway for the innate sensing of fungal pathogens.
      Title: Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables scavenger receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SCAVenger receptor (CD36 family) related
    NP_508919.2
    • Product from WormBase gene class scav;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5397699..5400584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076518.7 → NP_508919.2  SCAVenger receptor (CD36 family) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508919.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q11124
      Conserved Domains (1) summary
      pfam01130
      Location:19 → 546
      CD36; CD36 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q11124.2

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