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    cyp-29A2 Cytochrome P450 [ Caenorhabditis elegans ]

    Gene ID: 179550, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cyp-29A2
    Official Full Name
    Cytochrome P450
    Primary source
    WormBase:WBGene00011830
    Locus tag
    CELE_T19B10.1
    See related
    AllianceGenome:WB:WBGene00011830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. Is expressed in body wall musculature; hypodermis; intestine; nervous system; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cyp-29A2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (11217583..11219911)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Maelstrom domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein Neighboring gene Beta-galactosidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytochrome P450-dependent metabolism of eicosapentaenoic acid in the nematode Caenorhabditis elegans. Kulas J, et al. Arch Biochem Biophys, 2008 Apr 1. PMID 18282462
    2. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. Menzel R, et al. J Mol Biol, 2007 Jun 29. PMID 17499272
    3. SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension. Gao K, et al. Elife, 2019 Jan 15. PMID 30642431, Free PMC Article
    4. Eicosapentaenoic acid influences the pathogenesis of Candida albicans in Caenorhabditis elegans via inhibition of hyphal formation and stimulation of the host immune response. Mokoena NZ, et al. Med Microbiol Immunol, 2023 Oct. PMID 37672050, Free PMC Article
    5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome P450
    NP_505847.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11217583..11219911
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073446.5 → NP_505847.1  Cytochrome P450 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505847.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EC97
      Conserved Domains (1) summary
      pfam00067
      Location:37 → 495
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version

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