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    C11E4.6 ANK_REP_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181179, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C11E4.6
    Official Full Name
    ANK_REP_REGION domain-containing protein
    Primary source
    WormBase:WBGene00007520
    Locus tag
    CELE_C11E4.6
    See related
    AllianceGenome:WB:WBGene00007520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in neurons. Orthologous to human ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) and ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C11E4.6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (9610563..9617045)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PID domain-containing protein Neighboring gene Neuropeptide-Like Protein;Organic solute transporter alpha-like protein;Transmembrane protein Neighboring gene tRNA-Ala

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
    2. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
    3. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ANK_REP_REGION domain-containing protein
    NP_509620.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9610563..9617045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077219.6 → NP_509620.2  ANK_REP_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509620.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93203
      Conserved Domains (6) summary
      smart00454
      Location:833 → 901
      SAM; Sterile alpha motif
      cd00204
      Location:55 → 186
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00536
      Location:907 → 965
      SAM_1; SAM domain (Sterile alpha motif)
      pfam12796
      Location:66 → 164
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:135 → 164
      ANK; ANK repeat [structural motif]
      cl17171
      Location:1007 → 1151
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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