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    ptp-8 TYR_PHOSPHATASE_2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177510, updated on 9-Dec-2024

    Summary

    Official Symbol
    ptp-8
    Official Full Name
    TYR_PHOSPHATASE_2 domain-containing protein
    Primary source
    WormBase:WBGene00020444
    Locus tag
    CELE_T12B3.1
    See related
    AllianceGenome:WB:WBGene00020444
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in cilium assembly. Predicted to be active in cytoplasm. Orthologous to human PTPDC1 (protein tyrosine phosphatase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ptp-8 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (7382054..7384796)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene GP-PDE domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MOB kinase activator-like 3 Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    TYR_PHOSPHATASE_2 domain-containing protein
    NP_501178.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7382054..7384796
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068777.3NP_501178.1  TYR_PHOSPHATASE_2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501178.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9UAX0
      Conserved Domains (1) summary
      cd14506
      Location:64252
      PTP_PTPDC1; protein tyrosine phosphatase domain of PTP domain-containing protein 1