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    clec-88 C-type lectin domain-containing protein;C-type lectin domain-containing protein 88 [ Caenorhabditis elegans ]

    Gene ID: 174056, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-88
    Official Full Name
    C-type lectin domain-containing protein;C-type lectin domain-containing protein 88
    Primary source
    WormBase:WBGene00019606
    Locus tag
    CELE_K10B2.3
    See related
    AllianceGenome:WB:WBGene00019606
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Orthologous to several human genes including KLRF2 (killer cell lectin like receptor F2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-88 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (6365722..6367002)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein Asterix Neighboring gene Anillin-like protein 2 Neighboring gene Serine carboxypeptidase ctsa-4.1 Neighboring gene ncRNA Neighboring gene F-box domain-containing protein;F-box/WD repeat-containing protein lin-23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. Olson SK, et al. J Cell Biol, 2006 Jun 19. PMID 16785326, Free PMC Article
    2. Body stiffness is a mechanical property that facilitates contact-mediated mate recognition in Caenorhabditis elegans. Weng JW, et al. Curr Biol, 2023 Sep 11. PMID 37541249, Free PMC Article
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein;C-type lectin domain-containing protein 88
    NP_495283.2
    • Confirmed by transcript evidence
    NP_872010.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6365722..6367002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_182210.5 → NP_872010.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_872010.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ57
      Conserved Domains (1) summary
      smart00034
      Location:81 → 172
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)

    2. NM_062882.10 → NP_495283.2  C-type lectin domain-containing protein 88 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495283.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86NG3
      Conserved Domains (1) summary
      smart00034
      Location:81 → 218
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86NG3.1

    Gene LinkOut

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