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    pgl-2 P granule abnormality protein 2 [ Caenorhabditis elegans ]

    Gene ID: 182022, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pgl-2
    Official Full Name
    P granule abnormality protein 2
    Primary source
    WormBase:WBGene00003993
    Locus tag
    CELE_B0523.3
    See related
    AllianceGenome:WB:WBGene00003993
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in oogenesis. Located in P granule. Is expressed in germ line. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pgl-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (8670543..8675051, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene C-mannosyltransferase dpy-19 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene Protein flightless-1 homolog Neighboring gene ncRNA Neighboring gene tRNA-Trp Neighboring gene Nicotinamide N-methyltransferase Neighboring gene putative 3-ketoacyl-CoA thiolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PGL germ granule assembly protein is a base-specific, single-stranded RNase. Aoki ST, et al. Proc Natl Acad Sci U S A, 2016 Feb 2. PMID 26787882, Free PMC Article
    2. The PGL family proteins associate with germ granules and function redundantly in Caenorhabditis elegans germline development. Kawasaki I, et al. Genetics, 2004 Jun. PMID 15238518, Free PMC Article
    3. Walk the (germ) line. Jones DL. Cell Metab, 2009 Aug. PMID 19656483
    4. A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Curran SP, et al. Nature, 2009 Jun 25. PMID 19506556, Free PMC Article
    5. Specification of the germ line. Strome S. WormBook, 2005 Jul 28. PMID 18050414, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in oogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in P granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P granule abnormality protein 2
    NP_001370322.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8670543..8675051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382943.1 → NP_001370322.1  P granule abnormality protein 2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34266, P34267, P90737
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34266.2

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