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    sosi-1 DNA2/NAM7 helicase helicase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183377, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sosi-1
    Official Full Name
    DNA2/NAM7 helicase helicase domain-containing protein
    Primary source
    WormBase:WBGene00016565
    Locus tag
    CELE_C41D11.6
    See related
    AllianceGenome:WB:WBGene00016565
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be part of nuclear RNA-directed RNA polymerase complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sosi-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003279.8 (4460146..4462704, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein cmt-1 Neighboring gene Enhanced RNAI (RNA interference) Neighboring gene Enhanced RNAI (RNA interference) Neighboring gene ncRNA Neighboring gene Small integral membrane protein 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans. Rogers AK, et al. Cell Rep, 2020 Oct 20. PMID 33086057, Free PMC Article
    2. Terminal uridylyltransferases target RNA viruses as part of the innate immune system. Le Pen J, et al. Nat Struct Mol Biol, 2018 Sep. PMID 30104661, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear RNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA2/NAM7 helicase helicase domain-containing protein
    NP_491376.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4460146..4462704 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058975.1 → NP_491376.1  DNA2/NAM7 helicase helicase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491376.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01978
    Nucleotide Protein
    Heading Accession and Version

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