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    gcc-1 GRIP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180606, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gcc-1
    Official Full Name
    GRIP domain-containing protein
    Primary source
    WormBase:WBGene00002220
    Locus tag
    CELE_C15C7.2
    See related
    AllianceGenome:WB:WBGene00002220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in cytoplasm. Predicted to be active in Golgi apparatus. Is expressed in several structures, including anal sphincter muscle; excretory cell; hypodermis; nervous system; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gcc-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (3159940..3164424)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Putative syntaxin 6 Neighboring gene GDP-fucose protein O-fucosyltransferase 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and analysis of internal promoters in Caenorhabditis elegans operons. Huang P, et al. Genome Res, 2007 Oct. PMID 17712020, Free PMC Article
    2. The golgin coiled-coil proteins of the Golgi apparatus. Munro S. Cold Spring Harb Perspect Biol, 2011 Jun 1. PMID 21436057, Free PMC Article
    3. Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation. Gomes JE, et al. J Cell Biol, 2013 Aug 5. PMID 23918937, Free PMC Article
    4. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GRIP domain-containing protein
    NP_508543.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3159940..3164424
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076142.8 → NP_508543.2  GRIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508543.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18013
      Conserved Domains (3) summary
      smart00755
      Location:546 → 594
      Grip; golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
      COG1196
      Location:140 → 427
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02169
      Location:3 → 269
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    Nucleotide Protein
    Heading Accession and Version

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