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    C16A3.6 Protein MAK16 homolog [ Caenorhabditis elegans ]

    Gene ID: 175903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C16A3.6
    Official Full Name
    Protein MAK16 homolog
    Primary source
    WormBase:WBGene00015811
    Locus tag
    CELE_C16A3.6
    See related
    AllianceGenome:WB:WBGene00015811
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human MAK16 (MAK16 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C16A3.6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (6379449..6380669)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transcriptional repressor NF-X1 homolog Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein MAK16 homolog
    NP_498395.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6379449..6380669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065994.7 → NP_498395.1  Protein MAK16 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498395.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18035
      Conserved Domains (3) summary
      PLN00040
      Location:1 → 191
      PLN00040; Protein MAK16 homolog; Provisional
      pfam01778
      Location:6 → 115
      Ribosomal_L28e; Ribosomal L28e protein family
      pfam04874
      Location:148 → 231
      Mak16; Mak16 protein C-terminal region
    Nucleotide Protein
    Heading Accession and Version

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