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    nhr-125 Nuclear hormone receptor family member nhr-125 [ Caenorhabditis elegans ]

    Gene ID: 187520, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-125
    Official Full Name
    Nuclear hormone receptor family member nhr-125
    Primary source
    WormBase:WBGene00003715
    Locus tag
    CELE_R02D1.1
    See related
    AllianceGenome:WB:WBGene00003715
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-125 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (4322121..4325515, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Serpentine Receptor, class Z Neighboring gene Phenazine biosynthesis-like domain-containing protein Neighboring gene alcohol dehydrogenase Neighboring gene Acyl_transf_3 domain-containing protein Neighboring gene Recep_L_domain domain-containing protein;Receptor L-domain domain-containing protein Neighboring gene Glutaredoxin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mechanoreceptor DEG-1 regulates cold tolerance in Caenorhabditis elegans. Takagaki N, et al. EMBO Rep, 2020 Mar 4. PMID 32009302, Free PMC Article
    2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear hormone receptor family member nhr-125
    NP_001317832.1
    • Confirmed by transcript evidence
    NP_504194.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4322121..4325515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071793.6 → NP_504194.2  Nuclear hormone receptor family member nhr-125 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504194.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O17082
      Conserved Domains (2) summary
      smart00399
      Location:13 → 74
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:165 → 360
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor

    2. NM_001330851.3 → NP_001317832.1  Nuclear hormone receptor family member nhr-125 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H9N2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O17082.3

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