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    clec-7 C-type LECtin [ Caenorhabditis elegans ]

    Gene ID: 184314, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-7
    Official Full Name
    C-type LECtin
    Primary source
    WormBase:WBGene00017364
    Locus tag
    CELE_F10G2.3
    See related
    AllianceGenome:WB:WBGene00017364
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-positive bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (7328392..7330002)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein;G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene DUF19 domain-containing protein Neighboring gene UPF0376 protein F10G2.1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Per- and polyfluoroalkyl substances enhance Staphylococcus aureus pathogenicity and impair host immune response. Mangu JCK, et al. Environ Pollut, 2022 Dec 1. PMID 36181932
    2. Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria. Wan J, et al. Virulence, 2021 Dec. PMID 33372828, Free PMC Article
    3. Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes. Visvikis O, et al. Immunity, 2014 Jun 19. PMID 24882217, Free PMC Article
    4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-type LECtin
    NP_504865.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7328392..7330002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072464.5 → NP_504865.1  C-type LECtin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504865.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22955
      Conserved Domains (2) summary
      smart00034
      Location:25 → 152
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      cd00041
      Location:308 → 412
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    Nucleotide Protein
    Heading Accession and Version

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