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    bus-12 Transmembrane protein [ Caenorhabditis elegans ]

    Gene ID: 178283, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bus-12
    Official Full Name
    Transmembrane protein
    Primary source
    WormBase:WBGene00010442
    Locus tag
    CELE_JC8.12
    See related
    AllianceGenome:WB:WBGene00010442
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in intestine and seam cell. Orthologous to human SLC35D3 (solute carrier family 35 member D3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bus-12 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (13256186..13259076)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Zinc finger, CCHC-type Neighboring gene Transthyretin-like family protein Neighboring gene Transthyretin-like family protein Neighboring gene Transmembrane protein Neighboring gene Synaptojanin Neighboring gene Cleavage and polyadenylation specificity factor subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High concentrations of the anthelmintic diethylcarbamazine paralyze C. elegans independently of TRP-2. Datta R, et al. MicroPubl Biol, 2022. PMID 35622518, Free PMC Article
    2. Independent synchronized control and visualization of interactions between living cells and organisms. Rouger V, et al. Biophys J, 2014 May 20. PMID 24853738, Free PMC Article
    3. The hmsHFRS operon of Xenorhabdus nematophila is required for biofilm attachment to Caenorhabditis elegans. Drace K, et al. Appl Environ Microbiol, 2008 Jul. PMID 18515487, Free PMC Article
    4. Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans. Gravato-Nobre MJ, et al. Genetics, 2011 Jan. PMID 20980242, Free PMC Article
    5. Caenorhabditis elegans mutants resistant to attachment of Yersinia biofilms. Darby C, et al. Genetics, 2007 May. PMID 17339204, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in UDP-galactose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in UDP-glucose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein
    NP_001040957.1
    • Confirmed by transcript evidence
    NP_001040958.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13256186..13259076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047492.4 → NP_001040957.1  Transmembrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040957.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECW1

    2. NM_001047493.6 → NP_001040958.1  Transmembrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040958.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2EEM9
    Nucleotide Protein
    Heading Accession and Version

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