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    hrpu-2 RRM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177011, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hrpu-2
    Official Full Name
    RRM domain-containing protein
    Primary source
    WormBase:WBGene00022134
    Locus tag
    CELE_Y71G10AL.1
    See related
    AllianceGenome:WB:WBGene00022134
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in body wall musculature; intestinal cell; motor neurons; pharyngeal muscle cell; and somatic neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See hrpu-2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    13
    Sequence:
    Chromosome: IV; NC_003282.8 (2177896..2198937)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene P3 protein Neighboring gene Eukaryotic translation initiation factor 3 30 kDa subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans. Liu P, et al. J Neurosci, 2018 Jan 31. PMID 29217678, Free PMC Article
    2. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Akay A, et al. Dev Cell, 2017 Aug 7. PMID 28787591, Free PMC Article
    3. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    4. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    5. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. mutations of HRPU-2, a worm homolog of mammalian hnRNP U, result in dysfunction of a Slo2 potassium channel, which is critical to neuronal function
      Title: HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    RRM domain-containing protein
    NP_741334.3
    • Confirmed by transcript evidence
    NP_741335.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2177896..2198937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171899.6 → NP_741335.2  RRM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741335.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SPY1, Q8MXS3

    2. NM_171284.5 → NP_741334.3  RRM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741334.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SPY0, Q3V5J6
    Nucleotide Protein
    Heading Accession and Version

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