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    kbp-4 KNL (kinetochore null) Binding Protein [ Caenorhabditis elegans ]

    Gene ID: 175273, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kbp-4
    Official Full Name
    KNL (kinetochore null) Binding Protein
    Primary source
    WormBase:WBGene00022357
    Locus tag
    CELE_Y92C3B.1
    See related
    AllianceGenome:WB:WBGene00022357
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in kinetochore. Part of Ndc80 complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kbp-4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (1080901..1081300)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Splicing factor U2AF 65 kDa subunit Neighboring gene ncRNA Neighboring gene Ras-related protein Rab-18 Neighboring gene RING-type domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Gerson-Gurwitz A, et al. Cell, 2016 Apr 7. PMID 27020753, Free PMC Article
    2. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cheeseman IM, et al. Cell, 2006 Dec 1. PMID 17129783
    3. Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Cheerambathur DK, et al. Science, 2013 Dec 6. PMID 24231804, Free PMC Article
    4. Kinetochores: if you build it, they will come. DeLuca JG, et al. Curr Biol, 2004 Nov 9. PMID 15530383
    5. SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans. Yamamoto TG, et al. J Cell Biol, 2008 Oct 20. PMID 18936247, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ndc80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KNL (kinetochore null) Binding Protein
    NP_497330.2
    • Product from WormBase gene class kbp;
      Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1080901..1081300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064929.8 → NP_497330.2  KNL (kinetochore null) Binding Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497330.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N2X3
    Nucleotide Protein
    Heading Accession and Version

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