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    eif-3.C Eukaryotic translation initiation factor 3 subunit C [ Caenorhabditis elegans ]

    Gene ID: 172858, updated on 9-Dec-2024

    Summary

    Official Symbol
    eif-3.C
    Official Full Name
    Eukaryotic translation initiation factor 3 subunit C
    Primary source
    WormBase:WBGene00001226
    Locus tag
    CELE_T23D8.4
    See related
    AllianceGenome:WB:WBGene00001226
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3C (eukaryotic translation initiation factor 3 subunit C) and EIF3CL (eukaryotic translation initiation factor 3 subunit C like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See eif-3.C in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (9976426..9979662, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein mom-5 Neighboring gene Tetraspanin Neighboring gene Protein LTV1 homolog Neighboring gene Beta-catenin homolog sys-1 Neighboring gene ncRNA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation initiation factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in formation of cytoplasmic translation initiation complex IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic 43S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic 48S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of eukaryotic translation initiation factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Eukaryotic translation initiation factor 3 subunit C
    NP_492638.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9976426..9979662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060237.6NP_492638.1  Eukaryotic translation initiation factor 3 subunit C [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492638.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02328
      Conserved Domains (3) summary
      smart00753
      Location:735823
      PAM; PCI/PINT associated module
      pfam05470
      Location:31662
      eIF-3c_N; Eukaryotic translation initiation factor 3 subunit 8 N-terminus
      pfam12300
      Location:833897
      DUF3628; Protein of unknown function (DUF3628)