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    gsp-3 Serine/threonine-protein phosphatase PP1-gamma [ Caenorhabditis elegans ]

    Gene ID: 172082, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gsp-3
    Official Full Name
    Serine/threonine-protein phosphatase PP1-gamma
    Primary source
    WormBase:WBGene00021113
    Locus tag
    CELE_W09C3.6
    See related
    AllianceGenome:WB:WBGene00021113
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine phosphatase activity. Involved in several processes, including amoeboid sperm motility; egg-laying behavior; and male meiosis chromosome segregation. Located in chromatin; cytoplasm; and pseudopodium. Is expressed in germ line and sperm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gsp-3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (4709259..4710712, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene putative DNA-directed RNA polymerase III subunit RPC6 Neighboring gene Methyltransferase FkbM domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sperm Affects Head Sensory Neuron in Temperature Tolerance of Caenorhabditis elegans. Sonoda S, et al. Cell Rep, 2016 Jun 28. PMID 27320929
    2. Regulation of sperm-specific proteins by IFE-1, a germline-specific homolog of eIF4E, in C. elegans. Kawasaki I, et al. Mol Cells, 2011 Feb. PMID 21191815, Free PMC Article
    3. Characterization of a Caenorhabditis elegans glc seven-like phosphatase (gsp) orthologue from Haemonchus contortus (Nematoda). Campbell BE, et al. Mol Cell Probes, 2010 Aug. PMID 20153820
    4. Molecular characterisation of a male-specific serine/threonine phosphatase from Oesophagostomum dentatum (Nematoda: Strongylida), and functional analysis of homologues in Caenorhabditis elegans. Boag PR, et al. Int J Parasitol, 2003 Mar. PMID 12670516
    5. Maternal MEMI Promotes Female Meiosis II in Response to Fertilization in Caenorhabditis elegans. Ataeian M, et al. Genetics, 2016 Dec. PMID 27729423, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in amoeboid sperm motility IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in egg-laying behavior IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in male meiosis chromosome segregation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of pseudopodium assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in reproductive process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in pseudopodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in pseudopodium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serine/threonine-protein phosphatase PP1-gamma
    NP_491429.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4709259..4710712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059028.5 → NP_491429.1  Serine/threonine-protein phosphatase PP1-gamma [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491429.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02658
      Conserved Domains (2) summary
      smart00156
      Location:29 → 299
      PP2Ac; Protein phosphatase 2A homologues, catalytic domain
      cl13995
      Location:6 → 297
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O02658.1

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