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    Pnisr PNN interacting serine and arginine rich protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297942, updated on 27-Nov-2024

    Summary

    Official Symbol
    Pnisrprovided by RGD
    Official Full Name
    PNN interacting serine and arginine rich proteinprovided by RGD
    Primary source
    RGD:1307395
    See related
    EnsemblRapid:ENSRNOG00000008782 AllianceGenome:RGD:1307395
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sfrs18; Srsf18; RGD1307395
    Summary
    Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nuclear speck and presynaptic active zone. Orthologous to human PNISR (PNN interacting serine and arginine rich protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 340.1), Brain (RPKM 271.9) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pnisr in Genome Data Viewer
    Location:
    5q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (40190214..40219619)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (35395965..35422852)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (35991028..36017952)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478949 Neighboring gene ubiquitin specific peptidase 45 Neighboring gene large ribosomal subunit protein eL30-like Neighboring gene lysine acetyltransferase 2B, pseudogene 1 Neighboring gene coenzyme Q3 methyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC109235

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynaptic active zone IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    arginine/serine-rich protein PNISR
    Names
    PNN-interacting serine/arginine-rich protein
    serine/arginine-rich splicing factor 18
    splicing factor, arginine/serine-rich 18

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025274.2NP_001020445.2  arginine/serine-rich protein PNISR

      See identical proteins and their annotated locations for NP_001020445.2

      Status: PROVISIONAL

      Source sequence(s)
      CH473962
      UniProtKB/TrEMBL
      A6IIF0, A6IIF1, F1MAQ8
      Related
      ENSRNOP00000057854.3, ENSRNOT00000061139.6
      Conserved Domains (1) summary
      pfam15996
      Location:223380
      PNISR; Arginine/serine-rich protein PNISR

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      40190214..40219619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287296.1XP_063143366.1  arginine/serine-rich protein PNISR isoform X2

    2. XM_063287297.1XP_063143367.1  arginine/serine-rich protein PNISR isoform X3

    3. XM_063287295.1XP_063143365.1  arginine/serine-rich protein PNISR isoform X1

    RNA

    1. XR_010066349.1 RNA Sequence