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    Defb36 defensin beta 36 [ Mus musculus (house mouse) ]

    Gene ID: 266620, updated on 27-Nov-2024

    Summary

    Official Symbol
    Defb36provided by MGI
    Official Full Name
    defensin beta 36provided by MGI
    Primary source
    MGI:MGI:2385956
    See related
    Ensembl:ENSMUSG00000044863 AllianceGenome:MGI:2385956
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BD-36; mBD-36; Defb123
    Summary
    Predicted to be involved in defense response to bacterium and innate immune response. Predicted to be located in extracellular region. Orthologous to human DEFB123 (defensin beta 123). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 34.7) See more
    Orthologs
    NEW
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    Genomic context

    See Defb36 in Genome Data Viewer
    Location:
    2 H1; 2 75.41 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (152446247..152454649)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (152604327..152612729)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene defensin beta 19 Neighboring gene defensin beta 45 Neighboring gene protein kish-A pseudogene Neighboring gene predicted gene, 31618 Neighboring gene defensin beta 25 Neighboring gene rad and gem related GTP binding protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    beta-defensin 36
    Names
    defensin beta 123

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037247.4NP_001032324.1  beta-defensin 36 precursor

      See identical proteins and their annotated locations for NP_001032324.1

      Status: VALIDATED

      Source sequence(s)
      BX631384, DQ012042
      Consensus CDS
      CCDS38279.1
      UniProtKB/Swiss-Prot
      A3KGR4, Q3V491, Q8K3U4
      Related
      ENSMUSP00000059665.6, ENSMUST00000058086.6
      Conserved Domains (1) summary
      pfam13841
      Location:2453
      Defensin_beta_2; Beta defensin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      152446247..152454649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)