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    CG3829 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38000, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3829provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035091
    Locus tag
    Dmel_CG3829
    See related
    AllianceGenome:FB:FBgn0035091
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3829
    Summary
    Enables apolipoprotein binding activity. Involved in lipid export from cell. Is active in plasma membrane. Is expressed in several structures, including adult head; embryonic/larval crystal cell; embryonic/larval garland cell; embryonic/larval midgut; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 4. Orthologous to human SCARB1 (scavenger receptor class B member 1) and SCARB2 (scavenger receptor class B member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3829 in Genome Data Viewer
    Location:
    60E11-60E11; 2-107 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24986044..24990489)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20873567..20878012)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45252 Neighboring gene uncharacterized protein Neighboring gene epithelial membrane protein Neighboring gene zipper Neighboring gene unzipped

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to ovaries in Drosophila. Carrera P, et al. Development, 2024 May 1. PMID 38713014
    2. Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. Herboso L, et al. Int J Dev Biol, 2011. PMID 21948708
    3. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Jansen IE, et al. Genome Biol, 2017 Jan 30. PMID 28137300, Free PMC Article
    4. Selective maintenance of Drosophila tandemly arranged duplicated genes during evolution. Quijano C, et al. Genome Biol, 2008. PMID 19087263, Free PMC Article
    5. Systematic analysis of olfactory protein-protein interactions network of fruitfly, Drosophila melanogaster. Yang S, et al. Arch Insect Biochem Physiol, 2022 Jun. PMID 35249240

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to ovaries in Drosophila.
      Title: The CD36 scavenger receptor Bez regulates lipid redistribution from fat body to ovaries in Drosophila.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables apolipoprotein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables scavenger receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid export from cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3829-PA
    CG3829-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24986044..24990489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138148.4 → NP_611992.3  uncharacterized protein Dmel_CG3829, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611992.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961K6, Q9W0W9
      Related
      FBpp0072303
      Conserved Domains (1) summary
      pfam01130
      Location:91 → 546
      CD36; CD36 family

    2. NM_001299945.1 → NP_001286874.1  uncharacterized protein Dmel_CG3829, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286874.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961K6, Q9W0W9
      Conserved Domains (1) summary
      pfam01130
      Location:91 → 546
      CD36; CD36 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q961K6 Q961K6

    Gene LinkOut

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