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    CG42795 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41252, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42795provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261928
    Locus tag
    Dmel_CG42795
    See related
    AllianceGenome:FB:FBgn0261928
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12816; CG34108; CG3996; Dmel\CG42795
    Old locus tag
    Dmel_CG34108; Dmel_CG3996
    Summary
    Predicted to enable GTPase activator activity. Is expressed in adult head. Orthologous to human TBC1D30 (TBC1 domain family member 30). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42795 in Genome Data Viewer
    Location:
    86A1-86A2; 3-49 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10225690..10251277)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6051412..6076999)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sirtuin 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of EMS-induced mutations in Drosophila melanogaster by whole-genome sequencing. Blumenstiel JP, et al. Genetics, 2009 May. PMID 19307605, Free PMC Article
    2. Evolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteins. Gabernet-Castello C, et al. Mol Biol Cell, 2013 May. PMID 23485563, Free PMC Article
    3. Paternal diet affects differential gene expression, but not sperm competition, in sons. Zajitschek F, et al. Biol Lett, 2017 Feb. PMID 28202685, Free PMC Article
    4. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article
    5. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Bernards A. Biochim Biophys Acta, 2003 Mar 17. PMID 12618308

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42795-PA
    CG42795-PB
    CG42795-PC
    CG42795-PE
    CG42795-PF
    CG42795-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      10225690..10251277
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300342.1 → NP_001287271.1  uncharacterized protein Dmel_CG42795, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287271.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LH38
      Conserved Domains (4) summary
      PTZ00121
      Location:1112 → 2009
      PTZ00121; MAEBL; Provisional
      PTZ00449
      Location:2270 → 2610
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00566
      Location:224 → 443
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam15733
      Location:560 → 689
      DUF4682; Domain of unknown function (DUF4682)

    2. NM_001275526.2 → NP_001262455.1  uncharacterized protein Dmel_CG42795, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262455.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KG40
      Conserved Domains (4) summary
      pfam00566
      Location:268 → 443
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12361
      Location:1112 → 1415
      DBP; Duffy-antigen binding protein
      pfam15733
      Location:560 → 684
      DUF4682; Domain of unknown function (DUF4682)
      pfam16496
      Location:2376 → 2482
      SWIRM-assoc_2; SWIRM-associated domain at the N-terminal

    3. NM_001300343.1 → NP_001287272.1  uncharacterized protein Dmel_CG42795, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287272.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LH08
      Conserved Domains (4) summary
      PTZ00121
      Location:1112 → 2009
      PTZ00121; MAEBL; Provisional
      PTZ00449
      Location:2270 → 2610
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00566
      Location:224 → 443
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam15733
      Location:560 → 689
      DUF4682; Domain of unknown function (DUF4682)

    4. NM_001300341.1 → NP_001287270.1  uncharacterized protein Dmel_CG42795, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287270.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGZ2
      Conserved Domains (4) summary
      pfam00566
      Location:268 → 443
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12361
      Location:1112 → 1415
      DBP; Duffy-antigen binding protein
      pfam15733
      Location:560 → 684
      DUF4682; Domain of unknown function (DUF4682)
      pfam16496
      Location:2376 → 2482
      SWIRM-assoc_2; SWIRM-associated domain at the N-terminal

    5. NM_001202279.2 → NP_001189208.1  uncharacterized protein Dmel_CG42795, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189208.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JCW7
      Conserved Domains (4) summary
      pfam00566
      Location:268 → 443
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam12361
      Location:1112 → 1415
      DBP; Duffy-antigen binding protein
      pfam15733
      Location:560 → 684
      DUF4682; Domain of unknown function (DUF4682)
      pfam16496
      Location:2376 → 2482
      SWIRM-assoc_2; SWIRM-associated domain at the N-terminal

    6. NM_141731.3 → NP_649988.2  uncharacterized protein Dmel_CG42795, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649988.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VH10
      Conserved Domains (3) summary
      pfam00566
      Location:147 → 322
      RabGAP-TBC; Rab-GTPase-TBC domain
      pfam15733
      Location:439 → 563
      DUF4682; Domain of unknown function (DUF4682)
      pfam16496
      Location:2255 → 2361
      SWIRM-assoc_2; SWIRM-associated domain at the N-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JCW7 A0A0B4JCW7
    A0A0B4KG40 A0A0B4KG40
    A0A0B4LGZ2 A0A0B4LGZ2
    A0A0B4LH08 A0A0B4LH08
    A0A0B4LH38 A0A0B4LH38
    Q9VH10 Q9VH10

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