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    CG15543 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43647, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15543provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039799
    Locus tag
    Dmel_CG15543
    See related
    AllianceGenome:FB:FBgn0039799
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15543
    Summary
    Predicted to enable adenylate kinase activity. Predicted to be active in cytoplasm. Is expressed in adult head and spermatozoon. Orthologous to human AK8 (adenylate kinase 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15543 in Genome Data Viewer
    Location:
    100A3-100A3; 3-101 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30742880..30744474)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26568602..26570196)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4H2 Neighboring gene uncharacterized protein Neighboring gene Niemann-Pick type C-2g Neighboring gene Niemann-Pick type C-2h

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift. Cingolani P, et al. Front Genet, 2012. PMID 22435069, Free PMC Article
    2. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Ringrose L, et al. Dev Cell, 2003 Nov. PMID 14602076
    3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables adenylate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenylate kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15543-PA
    CG15543-PB
    NP_001287617.1
    NP_651822.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30742880..30744474
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300688.1 → NP_001287617.1  uncharacterized protein Dmel_CG15543, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287617.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K046, Q9VA43
      Conserved Domains (1) summary
      cl17190
      Location:89 → 213
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    2. NM_143565.3 → NP_651822.1  uncharacterized protein Dmel_CG15543, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651822.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K046, Q9VA43
      Related
      FBpp0085062
      Conserved Domains (1) summary
      cl17190
      Location:89 → 213
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K046 Q7K046
    Q9VA43 Q9VA43

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