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    fend forked end [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31843, updated on 2-Nov-2024

    Summary

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    Official Symbol
    fendprovided by FlyBase
    Official Full Name
    forked endprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030090
    Locus tag
    Dmel_CG12664
    See related
    AllianceGenome:FB:FBgn0030090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH56795; CG12664; Dmel\CG12664; Dromel_CG12664_FBtr0071349_ld14_mORF; ld14; LD14
    Summary
    Involved in motor neuron axon guidance. Is expressed in several structures, including abdominal lateral pentascolopidial chordotonal organ lch5; embryonic epidermis; embryonic heart cardioblast; larval central nervous system; and presumptive embryonic/larval central nervous system. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See fend in Genome Data Viewer
    Location:
    8C11-8C13; 1-26 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9121973..9135099, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9016006..9029132, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Adaptor Protein complex 1, gamma subunit Neighboring gene long non-coding RNA:CR45539 Neighboring gene long non-coding RNA:CR44517 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila identified by gain-of-function screening. Umemiya T, et al. J Neurobiol, 2002 Jun 5. PMID 11984842
    2. Novel tools for genetic manipulation of follicle stem cells in the Drosophila ovary reveal an integrin-dependent transition from quiescence to proliferation. Hartman TR, et al. Genetics, 2015 Apr. PMID 25680813, Free PMC Article
    3. The LARK RNA-binding protein selectively regulates the circadian eclosion rhythm by controlling E74 protein expression. Huang Y, et al. PLoS One, 2007 Oct 31. PMID 17971870, Free PMC Article
    4. Genome-wide screens for in vivo Tinman binding sites identify cardiac enhancers with diverse functional architectures. Jin H, et al. PLoS Genet, 2013. PMID 23326246, Free PMC Article
    5. Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. Hayden CA, et al. BMC Genomics, 2008 Feb 1. PMID 18237443, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila
      Title: Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila identified by gain-of-function screening.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forked end
    Names
    CG12664-PB
    CG12664-PC
    fend-PB
    fend-PC
    ld14

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9121973..9135099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272443.2 → NP_001259372.1  forked end, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259372.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9GNL3, Q9W387
      UniProtKB/TrEMBL
      M9PH27

    2. NM_132300.3 → NP_572528.1  forked end, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572528.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9GNL3, Q9W387
      UniProtKB/TrEMBL
      M9PH27
      Related
      FBpp0071284
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PH27 M9PH27
    Q8MS00 Q8MS00
    Q9GNL3.1 Q9GNL3

    Gene LinkOut

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