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    SPIK Shaker pollen inward K+ channel [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817099, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPIK
    Official Full Name
    Shaker pollen inward K+ channel
    Primary source
    TAIR:AT2G25600
    Locus tag
    AT2G25600
    See related
    Araport:AT2G25600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AKT6; F3N11.5; F3N11_5; Shaker pollen inward K+ channel
    Summary
    Encodes SPIK, a member of the Shaker family potassium ion (K+) channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). Mutant plants have impaired pollen-tube growth.
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    Genomic context

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    See SPIK in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (10894253..10898672)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Plant Tudor-like protein Neighboring gene DNA-directed RNA polymerase subunit beta Neighboring gene ATPase, F0/V0 complex, subunit C protein Neighboring gene DNA-binding protein phosphatase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis shaker pollen inward K(+) channel SPIK functions in SnRK1 complex-regulated pollen hydration on the stigma. Li DD, et al. J Integr Plant Biol, 2017 Sep. PMID 28636077
    2. Pollen tube development and competitive ability are impaired by disruption of a Shaker K(+) channel in Arabidopsis. Mouline K, et al. Genes Dev, 2002 Feb 1. PMID 11825875, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SnRK1 complex regulates SPIK expression, which functions in determining pollen hydration on the stigma
      Title: Arabidopsis shaker pollen inward K(+) channel SPIK functions in SnRK1 complex-regulated pollen hydration on the stigma.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128118.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inward rectifier potassium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables inward rectifier potassium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables potassium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables voltage-gated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Shaker pollen inward K+ channel
    NP_180131.3
    • Shaker pollen inward K+ channel (SPIK); FUNCTIONS IN: inward rectifier potassium channel activity, cyclic nucleotide binding, potassium channel activity; INVOLVED IN: pollen tube growth; LOCATED IN: membrane; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Potassium channel, voltage-dependent, EAG/ELK/ERG (InterPro:IPR003938), Protein of unknown function DUF3354 (InterPro:IPR021789), Ankyrin repeat-containing domain (InterPro:IPR020683), Ion transport (InterPro:IPR005821), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: K+ transporter 5 (TAIR:AT4G32500.1); Has 83148 Blast hits to 34215 proteins in 1581 species: Archae - 129; Bacteria - 8355; Metazoa - 40552; Fungi - 7952; Plants - 3977; Viruses - 1178; Other Eukaryotes - 21005 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10894253..10898672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128118.5 → NP_180131.3  Shaker pollen inward K+ channel [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180131.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GXE6, Q9SLA3
      UniProtKB/TrEMBL
      A0A5S9X1B6, A0A654F6T4
      Conserved Domains (2) summary
      PLN03192
      Location:38 → 888
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:576 → 607
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXE6.2

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