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    ARR7 response regulator 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838487, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARR7
    Official Full Name
    response regulator 7
    Primary source
    TAIR:AT1G19050
    Locus tag
    AT1G19050
    See related
    Araport:AT1G19050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F14D16.20; F14D16_20; response regulator 7
    Summary
    Encodes a member of the Arabidopsis response regulator (ARR) family, most closely related to ARR15. A two-component response regulator protein containing a phosphate accepting domain in the receiver domain but lacking a DNA binding domain in the output domain. Involved in response to cytokinin and meristem stem cell maintenance. Arr7 protein is stabilized by cytokinin.
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    Genomic context

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    See ARR7 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (6577833..6579314, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Neighboring gene hypothetical protein (DUF626) Neighboring gene F-box family protein Neighboring gene GINS complex protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosphorylation of Arabidopsis response regulator 7 (ARR7) at the putative phospho-accepting site is required for ARR7 to act as a negative regulator of cytokinin signaling. Lee DJ, et al. Planta, 2008 Feb. PMID 17938953
    2. Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response. Lee DJ, et al. Mol Genet Genomics, 2007 Feb. PMID 17061125
    3. Hormonal control of the shoot stem-cell niche. Zhao Z, et al. Nature, 2010 Jun 24. PMID 20577215
    4. WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators. Leibfried A, et al. Nature, 2005 Dec 22. PMID 16372013
    5. Response regulators implicated in His-to-Asp phosphotransfer signaling in Arabidopsis. Imamura A, et al. Proc Natl Acad Sci U S A, 1998 Mar 3. PMID 9482949, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ARR7 is direct targets of ABI4.ARR7 negatively regulate abscisic acid-mediated inhibition of germination.
      Title: ABI4 represses the expression of type-A ARRs to inhibit seed germination in Arabidopsis.
    2. activity of cytokinin and auxin directly converges on the promoters of two A-type ARABIDOPSIS RESPONSE REGULATOR (ARR) genes, ARR7 and ARR15, which are negative regulators of cytokinin signalling and have important meristematic functions
      Title: Hormonal control of the shoot stem-cell niche.
    3. Phosphorylation of ARR7 is necessary for ARR7-mediated cytokinin response.
      Title: Phosphorylation of Arabidopsis response regulator 7 (ARR7) at the putative phospho-accepting site is required for ARR7 to act as a negative regulator of cytokinin signaling.
    4. ARR7 mainly acts as a transcriptional repressor for a variety of early cytokinin-regulated genes encoding transcription factors, signal transmitters, plant development, and cellular metabolism.
      Title: Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101763.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphorelay response regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorelay signal transduction system TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cytokinin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    response regulator 7
    NP_173339.1
    • response regulator 7 (ARR7); CONTAINS InterPro DOMAIN/s: CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789); BEST Arabidopsis thaliana protein match is: response regulator 15 (TAIR:AT1G74890.1); Has 53636 Blast hits to 53063 proteins in 2702 species: Archae - 285; Bacteria - 47261; Metazoa - 20; Fungi - 584; Plants - 1468; Viruses - 6; Other Eukaryotes - 4012 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6577833..6579314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101763.3 → NP_173339.1  response regulator 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173339.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZWS7
      UniProtKB/TrEMBL
      A0A178WBA9, A0A654ECN6, Q2HIJ6
      Conserved Domains (1) summary
      cd17581
      Location:26 → 147
      REC_typeA_ARR; phosphoacceptor receiver (REC) domain of type A Arabidopsis response regulators (ARRs) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZWS7.1

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