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    Glycine cleavage T-protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826821, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Glycine cleavage T-protein family
    Primary source
    TAIR:AT4G12130
    Locus tag
    AT4G12130
    See related
    Araport:AT4G12130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16J13.200; F16J13_200
    Summary
    Encodes a mitochondrial COG0354 protein that requires folate for its function in Fe/S cluster biogenesis.
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (7263576..7265879)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Sec1/munc18-like (SM) proteins superfamily Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial and plastidial COG0354 proteins have folate-dependent functions in iron-sulphur cluster metabolism. Waller JC, et al. J Exp Bot, 2012 Jan. PMID 21984653, Free PMC Article
    2. A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life. Waller JC, et al. Proc Natl Acad Sci U S A, 2010 Jun 8. PMID 20489182, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_117283.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within iron-sulfur cluster assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Glycine cleavage T-protein family
    NP_192950.2
    • Glycine cleavage T-protein family; FUNCTIONS IN: aminomethyltransferase activity; INVOLVED IN: glycine catabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Folate-binding, YgfZ (InterPro:IPR017703), Glycine cleavage T-protein, N-terminal (InterPro:IPR006222), Glycine cleavage T-protein, C-terminal barrel (InterPro:IPR013977); Has 3767 Blast hits to 3765 proteins in 1151 species: Archae - 14; Bacteria - 1914; Metazoa - 108; Fungi - 149; Plants - 51; Viruses - 0; Other Eukaryotes - 1531 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7263576..7265879
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117283.3 → NP_192950.2  Glycine cleavage T-protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192950.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L733, Q9SZ78
      UniProtKB/TrEMBL
      A0A178UW21, A0A5S9XRJ3, A0A654FND1
      Conserved Domains (1) summary
      COG0354
      Location:35 → 377
      YgfZ; Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L733.1

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