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    PEL1 Eukaryotic release factor 1 (eRF1) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828876, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PEL1
    Official Full Name
    Eukaryotic release factor 1 (eRF1) family protein
    Primary source
    TAIR:AT4G27650
    Locus tag
    AT4G27650
    See related
    Araport:AT4G27650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PELOTA; T29A15.140; T29A15_140
    Summary
    Encodes Arabidopsis homolog of Drosophila pelota protein.
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    Genomic context

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    See PEL1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Sequence:
    Chromosome: 4; NC_003075.7 (13803268..13808031, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene GPCR-type G protein 2 Neighboring gene ARM repeat superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis. Vigh ML, et al. Nucleic Acids Res, 2022 Feb 22. PMID 35037064, Free PMC Article
    2. PELOTA and HBS1 suppress co-translational messenger RNA decay in Arabidopsis. Guo R, et al. Plant Direct, 2023 Dec. PMID 38149303, Free PMC Article
    3. mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth. Kong W, et al. Plant Physiol, 2021 Aug 3. PMID 33930167, Free PMC Article
    4. The No-go decay system degrades plant mRNAs that contain a long A-stretch in the coding region. Szádeczky-Kardoss I, et al. Plant Sci, 2018 Oct. PMID 30107878
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis.
      Title: Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis.
    2. mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth.
      Title: mRNA surveillance complex PELOTA-HBS1 regulates phosphoinositide-dependent protein kinase1 and plant growth.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001341877.1
    NM_118901.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA surveillance IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, no-go decay IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, non-stop decay IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Eukaryotic release factor 1 (eRF1) family protein
    NP_194495.3
    • PELOTA (PEL1); FUNCTIONS IN: translation release factor activity; INVOLVED IN: meiosis, translational termination, translation; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: eRF1 domain 2 (InterPro:IPR005141), eRF1 domain 3 (InterPro:IPR005142), eRF1 domain 1 (InterPro:IPR005140), Probable translation factor pelota (InterPro:IPR004405); BEST Arabidopsis thaliana protein match is: Eukaryotic release factor 1 (eRF1) family protein (TAIR:AT3G58390.1); Has 776 Blast hits to 774 proteins in 323 species: Archae - 255; Bacteria - 0; Metazoa - 140; Fungi - 159; Plants - 51; Viruses - 1; Other Eukaryotes - 170 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13803268..13808031 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341876.1 → NP_001329759.1  Eukaryotic release factor 1 (eRF1) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FPG8, Q9ZT87
      UniProtKB/TrEMBL
      A0A178V176, A0A5S9XX52
      Conserved Domains (1) summary
      cl30759
      Location:1 → 371
      PelA; Stalled ribosome rescue protein Dom34, pelota family [Translation, ribosomal structure and biogenesis]

    2. NM_118901.5 → NP_194495.3  Eukaryotic release factor 1 (eRF1) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194495.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FPG8, Q9ZT87
      UniProtKB/TrEMBL
      A0A178V176, A0A5S9XX52
      Conserved Domains (1) summary
      cl30759
      Location:1 → 371
      PelA; Stalled ribosome rescue protein Dom34, pelota family [Translation, ribosomal structure and biogenesis]

    3. NM_001341877.1 → NP_001329760.1  Eukaryotic release factor 1 (eRF1) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FPG8, Q9ZT87
      UniProtKB/TrEMBL
      A0A178V176, A0A5S9XX52
      Conserved Domains (1) summary
      cl30759
      Location:1 → 371
      PelA; Stalled ribosome rescue protein Dom34, pelota family [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZT87.1

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