PGR3 proton gradient regulation 3 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PGR3
Official Full Name: proton gradient regulation 3
Primary source: TAIR:AT4G31850
Locus tag: AT4G31850
See related: Araport:AT4G31850
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F11C18.50; F11C18_50; proton gradient regulation 3
Summary: encodes a protein containing 27 pentatrico-peptide repeat (PPR) motifs
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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The Pentatricopeptide Repeat Protein PGR3 Is Required for the Translation of petL and ndhG by Binding Their 5' UTRs.
Title: The Pentatricopeptide Repeat Protein PGR3 Is Required for the Translation of petL and ndhG by Binding Their 5' UTRs.
RNA-binding protein PGR3 (PGR3) acts in the rpl14-rps8 intergenic region to stabilize a 3'-RNA terminus and stimulate rps8 translation.
Title: Unexpected functional versatility of the pentatricopeptide repeat proteins PGR3, PPR5 and PPR10.
The mechanism underlying the functional versatility of Arabidopsis thaliana proton gradient regulation3, was investigated.
Title: Mutagenesis of individual pentatricopeptide repeat motifs affects RNA binding activity and reveals functional partitioning of Arabidopsis PROTON gradient regulation3.
The C-terminal PPR repeat of PGR3 is required for activating translation but not for RNA binding. PGR3 binds to the 5' UTRs of petL and ndhA mRNA.
Title: PROTON GRADIENT REGULATION 3 recognizes multiple targets with limited similarity and mediates translation and RNA stabilization in plastids.

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NM_119335.2

Function	Evidence Code	Pubs
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA stabilization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within plastid translation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within translation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_194913.1

proton gradient regulation 3 (PGR3); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G06920.1); Has 108367 Blast hits to 15783 proteins in 329 species: Archae - 17; Bacteria - 129; Metazoa - 1401; Fungi - 2165; Plants - 100462; Viruses - 0; Other Eukaryotes - 4193 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain