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    PP7 serine/threonine phosphatase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836507, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PP7
    Official Full Name
    serine/threonine phosphatase 7
    Primary source
    TAIR:AT5G63870
    Locus tag
    AT5G63870
    See related
    Araport:AT5G63870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPP7; MGI19.12; MGI19_12; serine/threonine phosphatase 7
    Summary
    Encodes a nuclear localized serine/threonine phosphatase that appears to be regulated by redox activity and is a positive regulator of cryptochrome mediated blue light signalling.
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    Genomic context

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    See PP7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (25561070..25563316, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene amino acid permease 4 Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene SNF7 family protein Neighboring gene histidinol dehydrogenase Neighboring gene Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PP7 is a positive regulator of blue light signaling in Arabidopsis. Møller SG, et al. Plant Cell, 2003 May. PMID 12724537, Free PMC Article
    2. Expression and characterization of PP7, a novel plant protein Ser/Thr phosphatase distantly related to RdgC/PPEF and PP5. Kutuzov MA, et al. FEBS Lett, 1998 Nov 27. PMID 9862444
    3. An Arabidopsis mutant hypersensitive to red and far-red light signals. Genoud T, et al. Plant Cell, 1998 Jun. PMID 9634578, Free PMC Article
    4. Hypersensitive to red and blue 1 and its modification by protein phosphatase 7 are implicated in the control of Arabidopsis stomatal aperture. Sun X, et al. PLoS Genet, 2012. PMID 22589732, Free PMC Article
    5. The protein phosphatase 7 regulates phytochrome signaling in Arabidopsis. Genoud T, et al. PLoS One, 2008 Jul 16. PMID 18628957, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. We propose that a modification of HRB1 by PP7 under blue light is essential to acquire a proper conformation or to bring in new components for the assembly of a functional HRB1 protein complex
      Title: Hypersensitive to red and blue 1 and its modification by protein phosphatase 7 are implicated in the control of Arabidopsis stomatal aperture.
    2. NDPK2 plays a critical role in the AtPP7 regulation of the phytochrome pathway
      Title: The protein phosphatase 7 regulates phytochrome signaling in Arabidopsis.
    3. AtPP7 interacts with calmodulin and with a heat shock transcription factor.
      Title: Calmodulin-binding protein phosphatase PP7 is involved in thermotolerance in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125782.3
    NM_180927.4
    NM_180928.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within blue light signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within red, far-red light phototransduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine phosphatase 7
    NP_568979.1
    • serine/threonine phosphatase 7 (PP7); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: hydrolases;protein serine/threonine phosphatases (TAIR:AT1G48120.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_851258.2
    • serine/threonine phosphatase 7 (PP7); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: hydrolases;protein serine/threonine phosphatases (TAIR:AT1G48120.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_851259.1
    • serine/threonine phosphatase 7 (PP7); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: hydrolases;protein serine/threonine phosphatases (TAIR:AT1G48120.1); Has 6565 Blast hits to 6502 proteins in 500 species: Archae - 78; Bacteria - 264; Metazoa - 2313; Fungi - 1308; Plants - 955; Viruses - 0; Other Eukaryotes - 1647 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25561070..25563316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180928.2 → NP_851259.1  serine/threonine phosphatase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851259.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49346, Q3E865, Q9FN02
      UniProtKB/TrEMBL
      A0A178UB38, A0A5S9YHA3
      Conserved Domains (1) summary
      cd07418
      Location:11 → 388
      MPP_PP7; PP7, metallophosphatase domain

    2. NM_180927.4 → NP_851258.2  serine/threonine phosphatase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851258.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49346, Q3E865, Q9FN02
      UniProtKB/TrEMBL
      A0A178UB38, A0A5S9YHA3
      Conserved Domains (1) summary
      cd07418
      Location:11 → 388
      MPP_PP7; PP7, metallophosphatase domain

    3. NM_125782.3 → NP_568979.1  serine/threonine phosphatase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568979.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FN02
      Conserved Domains (2) summary
      pfam00149
      Location:79 → 298
      Metallophos; Calcineurin-like phosphoesterase
      cl13995
      Location:11 → 297
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FN02.1

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