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    UBC3 ubiquitin-conjugating enzyme 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836374, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBC3
    Official Full Name
    ubiquitin-conjugating enzyme 3
    Primary source
    TAIR:AT5G62540
    Locus tag
    AT5G62540
    See related
    Araport:AT5G62540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K19B1.15; K19B1_15; ubiquitin-conjugating enzyme 3
    Summary
    Encodes a protein predicted to be an E2 ubiquitin conjugating enzyme. It appears homologous to the RAD6 protein in yeast implicated in histone ubiquitination, but, UBC3 has not been experimentally associated with this process.
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    Genomic context

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    See UBC3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (25103934..25105619)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene aldehyde dehydrogenase 12A1 Neighboring gene uncharacterized protein Neighboring gene microtubule-associated futsch-like protein Neighboring gene RING/U-box superfamily protein with ARM repeat domain-containing protein Neighboring gene Calmodulin binding protein-like protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Kraft E, et al. Plant Physiol, 2005 Dec. PMID 16339806, Free PMC Article
    2. Protein degradation in signaling. Callis J, et al. Curr Opin Plant Biol, 2000 Oct. PMID 11019805
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_125648.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme 3
    NP_568956.1
    • ubiquitin-conjugating enzyme 3 (UBC3); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquiting-conjugating enzyme 2 (TAIR:AT2G02760.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25103934..25105619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125648.3 → NP_568956.1  ubiquitin-conjugating enzyme 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568956.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42746, Q4TZ06, Q8H1P1, Q94AD2
      UniProtKB/TrEMBL
      A0A178ULQ4, A0A5S9YGW7, A0A7G2FI98
      Conserved Domains (1) summary
      COG5078
      Location:1 → 148
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42746.1

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