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    PRH75 DEAD box RNA helicase (PRH75) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836340, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PRH75
    Official Full Name
    DEAD box RNA helicase (PRH75)
    Primary source
    TAIR:AT5G62190
    Locus tag
    AT5G62190
    See related
    Araport:AT5G62190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MMI9.2; MMI9_2; RNA HELICASE
    Summary
    DEAD/DEAH box RNA helicase PRH75
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    Genomic context

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    See PRH75 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (24980268..24984044, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene LOW protein: M-phase inducer phosphatase-like protein Neighboring gene carboxyesterase 20 Neighboring gene Embryo-specific protein 3, (ATS3) Neighboring gene Embryo-specific protein 3, (ATS3)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DEAD-Box RNA Helicase AtRH7/PRH75 Participates in Pre-rRNA Processing, Plant Development and Cold Tolerance in Arabidopsis. Huang CK, et al. Plant Cell Physiol, 2016 Jan. PMID 26637537
    2. A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature. Liu Y, et al. PLoS One, 2016. PMID 27116354, Free PMC Article
    3. An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE. Nayak NR, et al. Plant Cell, 2013 Jul. PMID 23903319, Free PMC Article
    4. PRH75, a new nucleus-localized member of the DEAD-box protein family from higher plants. Lorković ZJ, et al. Mol Cell Biol, 1997 Apr. PMID 9121476, Free PMC Article
    5. Use of fluorescent protein tags to study nuclear organization of the spliceosomal machinery in transiently transformed living plant cells. Lorković ZJ, et al. Mol Biol Cell, 2004 Jul. PMID 15133128, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The study indicated that AtRH7 participates in rRNA biogenesis and is also involved in plant development and cold tolerance in Arabidopsis.
      Title: The DEAD-Box RNA Helicase AtRH7/PRH75 Participates in Pre-rRNA Processing, Plant Development and Cold Tolerance in Arabidopsis.
    2. This study identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (AtCSP3), which is an RNA chaperone involved in cold adaptation. [AtRH7]
      Title: A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature.
    3. Data indicate that human PROTEIN ISOASPARTYL METHYLTRANSFERASE (PIMT) can initiate isoAsp conversion to Asp, and is able to restore Arabidopsis PRH75's complex biochemical activity provided isoAsp formation has not led to conformational alterations.
      Title: An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125613.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DEAD/H-box RNA helicase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within RNA metabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DEAD box RNA helicase (PRH75)
    NP_201025.1
    • PRH75; FUNCTIONS IN: DEAD/H-box RNA helicase binding, ATP-dependent helicase activity; INVOLVED IN: RNA metabolic process; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RNA helicase, ATP-dependent, DEAD-box, conserved site (InterPro:IPR000629), GUCT (InterPro:IPR012562), RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEAD box RNA helicase (RH3) (TAIR:AT5G26742.2); Has 57587 Blast hits to 49572 proteins in 3210 species: Archae - 795; Bacteria - 24538; Metazoa - 10953; Fungi - 6002; Plants - 4052; Viruses - 90; Other Eukaryotes - 11157 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24980268..24984044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125613.3 → NP_201025.1  DEAD box RNA helicase (PRH75) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201025.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39189, Q94BX7, Q9LVB7
      UniProtKB/TrEMBL
      A0A178UJQ9, A0A5S9YGH0, A0A654GD89
      Conserved Domains (2) summary
      COG0513
      Location:99 → 479
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      pfam08152
      Location:533 → 624
      GUCT; GUCT (NUC152) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39189.2

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