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    HB-3 homeobox 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831367, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HB-3
    Official Full Name
    homeobox 3
    Primary source
    TAIR:AT5G15150
    Locus tag
    AT5G15150
    See related
    Araport:AT5G15150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATHB-3; ATHB3; F8M21.40; F8M21_40; HAT7; homeobox 3; HOMEOBOX FROM ARABIDOPSIS THALIANA 7; HOMEOBOX PROTEIN
    Summary
    homeobox-containing gene with an unusual feature: a leucine zipper motif adjacent to the carboxyl-terminal of the homeodomain structure. This gene is expressed primarily in the cortex of the root and the stem.
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    Genomic context

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    See HB-3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (4913699..4915976, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene WRKY DNA-binding protein 72 Neighboring gene Galactose mutarotase-like superfamily protein Neighboring gene ncRNA Neighboring gene BANQUO 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new homeobox-leucine zipper gene from Arabidopsis thaliana. Mattsson J, et al. Plant Mol Biol, 1992 Mar. PMID 1349836
    2. DNA-binding and dimerization preferences of Arabidopsis homeodomain-leucine zipper transcription factors in vitro. Johannesson H, et al. Plant Mol Biol, 2001 Jan. PMID 11247607
    3. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_121519.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    homeobox 3
    NP_568309.2
    • homeobox 3 (HB-3); FUNCTIONS IN: sequence-specific DNA binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Helix-turn-helix motif, lambda-like repressor (InterPro:IPR000047), Homeodomain-like (InterPro:IPR009057), Leucine zipper, homeobox-associated (InterPro:IPR003106), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeobox protein 20 (TAIR:AT3G01220.1); Has 11268 Blast hits to 11217 proteins in 570 species: Archae - 0; Bacteria - 6; Metazoa - 8826; Fungi - 177; Plants - 2030; Viruses - 5; Other Eukaryotes - 224 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4913699..4915976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121519.3 → NP_568309.2  homeobox 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568309.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q00466, Q0WNS2, Q9LXG6
      UniProtKB/TrEMBL
      A0A178UMX8, A0A5S9Y4U8, B5RID5
      Conserved Domains (2) summary
      smart00389
      Location:115 → 168
      HOX; Homeodomain
      pfam02183
      Location:170 → 208
      HALZ; Homeobox associated leucine zipper
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q00466.4

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