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    BGLU21 Glycosyl hydrolase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842944, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BGLU21
    Official Full Name
    Glycosyl hydrolase superfamily protein
    Primary source
    TAIR:AT1G66270
    Locus tag
    AT1G66270
    See related
    Araport:AT1G66270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6J19.2
    Summary
    BGLU21 encodes a beta-glucosidase that has a high level of activity against the naturally occuring secondary metabolite scopolin. Recombinant BGLU21 produced in insect cells shows lower levels of activity using the structurally similar substrates esculin (33%) and 4-MU-glucoside (9%). BGLU21 is glycosylated in planta and has a C-terminal ER retention signal. Transcript analysis as well as protein extraction and western blotting from various plant organs suggest that BGLU21 is only present in roots and seedlings. Transcript levels increase in response to cold, auxin (2,4-D), and methyl jasmonate treatments.
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    Genomic context

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    See BGLU21 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (24699868..24703166, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene Glycosyl hydrolase superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phosphate-starvation inducible beta-glucosidase gene (psr3.2) isolated from Arabidopsis thaliana is a member of a distinct subfamily of the BGA family. Malboobi MA, et al. Plant Mol Biol, 1997 May. PMID 9177312
    2. Isolation of cDNA clones of genes with altered expression levels in phosphate-starved Brassica nigra suspension cells. Malboobi MA, et al. Plant Mol Biol, 1995 Aug. PMID 7640358
    3. Scopolin-hydrolyzing beta-glucosidases in roots of Arabidopsis. Ahn YO, et al. Plant Cell Physiol, 2010 Jan. PMID 19965874
    4. Post-transcriptional control of GRF transcription factors by microRNA miR396 and GIF co-activator affects leaf size and longevity. Debernardi JM, et al. Plant J, 2014 Aug. PMID 24888433
    5. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105298.4
    NM_179517.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables beta-glucosidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cellular response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to phosphate starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to phosphate starvation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within coumarin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Glycosyl hydrolase superfamily protein
    NP_176801.1
    • BGLU21; FUNCTIONS IN: beta-glucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds; INVOLVED IN: cellular response to phosphate starvation, response to salt stress, cellular response to cold, cellular response to salt stress, response to osmotic stress; LOCATED IN: vacuole, membrane; EXPRESSED IN: root, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: Glycosyl hydrolase superfamily protein (TAIR:AT1G66280.1); Has 11188 Blast hits to 10882 proteins in 1457 species: Archae - 140; Bacteria - 7714; Metazoa - 698; Fungi - 202; Plants - 1441; Viruses - 0; Other Eukaryotes - 993 (source: NCBI BLink).
    NP_849848.1
    • BGLU21; FUNCTIONS IN: beta-glucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds; INVOLVED IN: cellular response to phosphate starvation, response to salt stress, cellular response to cold, cellular response to salt stress, response to osmotic stress; LOCATED IN: vacuole, membrane; EXPRESSED IN: root, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: Glycosyl hydrolase superfamily protein (TAIR:AT1G66280.1); Has 11164 Blast hits to 10873 proteins in 1456 species: Archae - 140; Bacteria - 7708; Metazoa - 683; Fungi - 200; Plants - 1442; Viruses - 0; Other Eukaryotes - 991 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24699868..24703166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105298.4 → NP_176801.1  Glycosyl hydrolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176801.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23656, Q3ECH6, Q9C525
      UniProtKB/TrEMBL
      A0A178WA93, A0A5S9WQ98, A0A7G2E3M9
      Conserved Domains (1) summary
      cl23725
      Location:38 → 511
      Glyco_hydro; Glycosyl hydrolases

    2. NM_179517.2 → NP_849848.1  Glycosyl hydrolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849848.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E3M9
      Conserved Domains (1) summary
      cl23725
      Location:37 → 507
      Glyco_hydro_1; Glycosyl hydrolase family 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C525.1

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