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    PHE1 MADS-box transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842841, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PHE1
    Official Full Name
    MADS-box transcription factor family protein
    Primary source
    TAIR:AT1G65330
    Locus tag
    AT1G65330
    See related
    Araport:AT1G65330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AGAMOUS-like 37; AGL37; PHERES1; T8F5.11; T8F5_11
    Summary
    Type I MADS-box protein, regulated by MEA and FIE, expressed transiently after fertilization in embryo and endosperm.
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    Genomic context

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    See PHE1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (24266257..24267336, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene xyloglucan endotransglucosylase/hydrolase 17 Neighboring gene Cystathionine beta-synthase (CBS) family protein Neighboring gene cytochrome P450, family 96, subfamily A, polypeptide 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons. Batista RA, et al. Elife, 2019 Dec 2. PMID 31789592, Free PMC Article
    2. Control of PHERES1 imprinting in Arabidopsis by direct tandem repeats. Villar CBR, et al. Mol Plant, 2009 Jul. PMID 19825646
    3. Mechanism of PHERES1 imprinting in Arabidopsis. Makarevich G, et al. J Cell Sci, 2008 Mar 15. PMID 18303047
    4. The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting. Köhler C, et al. Nat Genet, 2005 Jan. PMID 15619622
    5. The Polycomb-group protein MEDEA regulates seed development by controlling expression of the MADS-box gene PHERES1. Köhler C, et al. Genes Dev, 2003 Jun 15. PMID 12815071, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the imprinted Arabidopsis thaliana MADS-box TF PHERES1 (PHE1) is a master regulator of paternally expressed imprinted genes, as well as of non-imprinted key regulators of endosperm development.
      Title: The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons.
    2. Study shows that PHERES1 is regulated by genomic imprinting, which is likely caused by the presence of repeat sequences in the proximity of the PHERES1 locus.
      Title: Control of PHERES1 imprinting in Arabidopsis by direct tandem repeats.
    3. AtUBP26 is required for normal seed development and the repression of PHE1
      Title: UBIQUITIN-SPECIFIC PROTEASE 26 is required for seed development and the repression of PHERES1 in Arabidopsis.
    4. Evidence that silencing of the maternal PHERES1 allele depends on a distantly located region downstream of the PHERES1 locus.
      Title: Mechanism of PHERES1 imprinting in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_105207.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in pollen tube IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MADS-box transcription factor family protein
    NP_176712.1
    • PHERES1 (PHE1); CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 38 (TAIR:AT1G65300.1); Has 3933 Blast hits to 3931 proteins in 449 species: Archae - 0; Bacteria - 0; Metazoa - 161; Fungi - 84; Plants - 3665; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24266257..24267336 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105207.2 → NP_176712.1  MADS-box transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176712.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80805, Q84JV4, Q84JW5, Q84VN9, Q84VP0, Q84VP1
      UniProtKB/TrEMBL
      A0A178W2S5, A0A5S9WPI0, A0A654EMR7
      Conserved Domains (1) summary
      cd00266
      Location:1 → 84
      MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80805.1

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